diff --git a/toonz/sources/CMakeLists.txt b/toonz/sources/CMakeLists.txt
index 00567ca..30b4386 100644
--- a/toonz/sources/CMakeLists.txt
+++ b/toonz/sources/CMakeLists.txt
@@ -312,6 +312,16 @@ elseif(UNIX)
 endif()
 
 
+include(TestBigEndian)
+test_big_endian(_SYSTEM_BIG_ENDIAN)
+if(_SYSTEM_BIG_ENDIAN)
+    add_definitions(-DTNZ_LITTLE_ENDIAN=0)
+else()
+    add_definitions(-DTNZ_LITTLE_ENDIAN=1)
+endif()
+unset(_SYSTEM_BIG_ENDIAN)
+
+
 set(C_WARNINGS)
 set(CXX_WARNINGS)
 
diff --git a/toonz/sources/include/tmachine.h b/toonz/sources/include/tmachine.h
index 66c7e70..d7a8944 100644
--- a/toonz/sources/include/tmachine.h
+++ b/toonz/sources/include/tmachine.h
@@ -4,21 +4,21 @@
 #define T_MACHINE_INCLUDED
 
 #if defined(_WIN32) || defined(i386)
-#define TNZ_LITTLE_ENDIAN 1
 #define TNZ_MACHINE_CHANNEL_ORDER_BGRM 1
 #elif defined(__sgi)
-#define TNZ_LITTLE_ENDIAN 0
 #define TNZ_MACHINE_CHANNEL_ORDER_MBGR 1
 #elif defined(LINUX)
-#define TNZ_LITTLE_ENDIAN 1
 #define TNZ_MACHINE_CHANNEL_ORDER_BGRM 1
 #elif defined(MACOSX)
-#define TNZ_LITTLE_ENDIAN 0
 #define TNZ_MACHINE_CHANNEL_ORDER_MRGB 1
 #else
 @UNKNOW PLATFORM @
 #endif
 
+#if !defined(TNZ_LITTLE_ENDIAN)
+#error "TNZ_LITTLE_ENDIAN not defined!"
+#endif
+
 #ifndef WIN32
 #ifdef MACOSX
 #define _finite isfinite
diff --git a/toonz/sources/include/toonz4.6/machine.h b/toonz/sources/include/toonz4.6/machine.h
index 7f02ef5..e9bf6f6 100644
--- a/toonz/sources/include/toonz4.6/machine.h
+++ b/toonz/sources/include/toonz4.6/machine.h
@@ -11,31 +11,24 @@
 #define SCANNER_DEVNAME "/dev/scanner"
 #define DDR_DEVNAME     "/dev/ddr"
 #endif
-
-
-#ifdef __sgi
-#define TNZ_LITTLE_ENDIAN 0
-#else
-#define TNZ_LITTLE_ENDIAN 1
-#endif
 */
 
 #if defined(_WIN32) || defined(i386)
-#define TNZ_LITTLE_ENDIAN 1
 #define TNZ_MACHINE_CHANNEL_ORDER_BGRM 1
 #elif defined(__sgi)
-#define TNZ_LITTLE_ENDIAN 0
 #define TNZ_MACHINE_CHANNEL_ORDER_MBGR 1
 #elif defined(LINUX)
-#define TNZ_LITTLE_ENDIAN 1
 #define TNZ_MACHINE_CHANNEL_ORDER_BGRM 1
 #elif defined(MACOSX)
-#define TNZ_LITTLE_ENDIAN 0
 #define TNZ_MACHINE_CHANNEL_ORDER_MRGB 1
 #else
 @UNKNOW PLATFORM @
 #endif
 
+#if !defined(TNZ_LITTLE_ENDIAN)
+#error "TNZ_LITTLE_ENDIAN not defined!"
+#endif
+
 /*
 #ifdef WIN32
 #define TNZ_MACHINE_CHANNEL_ORDER_BGRM 1